Biotin Anti-Human CD127/IL-7RA Antibody[A019D5]
Produktgrößen
25 ug
£151,00
E-AB-F1152B-25UG
100 ug
£374,00
E-AB-F1152B-100UG
Über dieses Produkt
- SKU:
- E-AB-F1152B
- Zusätzliche Namen:
- CD127;CDw127;IL-7RA;IL-7RA Alpha;Interleukin-7 receptor subunit alpha
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- A019D5
- Klonalität:
- Monoclonal
- Konjugat:
- Biotin
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor A Alpha chain or IL-7RA Alpha. It forms a heterodimer with the common G Gamma chain (G Gammac or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
- Host:
- Mouse
- Immunogen:
- CD127
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:il_7ra_antibody[a019d5]-e_ab_f1152b