AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3]
Produktgrößen
25 ug
£66,00
E-AB-F11330-25UG
100 ug
£89,00
E-AB-F11330-100UG
1 mg
£171,00
E-AB-F11330-1MG
5 mg
£490,00
E-AB-F11330-5MG
25 mg
£1515,00
E-AB-F11330-25MG
50 mg
£2247,00
E-AB-F11330-50MG
100 mg
£3211,00
E-AB-F11330-100MG
Über dieses Produkt
- SKU:
- E-AB-F11330
- Zusätzliche Namen:
- B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
- Anwendung:
- Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- 29E.2A3
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-G Gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- Host:
- Mouse
- Immunogen:
- PD-L1|Recombinant Human PD-L1 protein
- Isotyp:
- IgG2b, kappa
- Reinheit:
- >98%
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:a18CCG