APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
Produktgrößen
50 tests
£93,00
E-AB-F1132E-50TESTS
100 tests
£120,00
E-AB-F1132E-100TESTS
2 x 100 tests
£155,00
E-AB-F1132E-2X100TESTS
Über dieses Produkt
- SKU:
- E-AB-F1132E
- Zusätzliche Namen:
- B7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 10F.9G2
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 5 ul/test
- Weitere Details:
- CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-G Gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-G Gamma, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- Host:
- Rat
- Immunogen:
- CD274/PD-L1
- Isotyp:
- IgG2b, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:rr5SO8