APC Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Produktgrößen
25 ug
£117,00
E-AB-F1131UE-25UG
100 ug
£226,00
E-AB-F1131UE-100UG
Über dieses Produkt
- SKU:
- E-AB-F1131UE
- Zusätzliche Namen:
- Programmed Death-1;PD-1
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 29F.1A12
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
- Host:
- Rat
- Immunogen:
- CD279/PD-1
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:pd_1_antibody[29f.1a12]-e_ab_f1131ue