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Antikörper

Purified Anti-Human CD279/PD-1 Antibody[J116], Functional Grade

Produktgrößen
100 ug
£89,00
E-AB-F11290-100UG
1 mg
£171,00
E-AB-F11290-1MG
5 mg
£490,00
E-AB-F11290-5MG
25 mg
£1515,00
E-AB-F11290-25MG
50 mg
£2247,00
E-AB-F11290-50MG
100 mg
£3211,00
E-AB-F11290-100MG
Über dieses Produkt
SKU:
E-AB-F11290
Zusätzliche Namen:
Programmed Death-1,PD-1
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
J116
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human CD279 protein
Isotyp:
IgG1, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
Molt-4 were activated for 4 hour with MIX, then stained with 0.2 ug Purified Anti-Human CD279 Antibody[J116], Functional Grade (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control(Left), followed by APC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Jurkat were activated for 4 hour with MIX, then stained with 0.2 ug Purified Anti-Human CD83 Antibody[HB15e] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug AF/LE Purified Anti-Mouse CD86 Antibody[GL-1] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Rat IgG Secondary Antibody.
Mouse peritoneal macrophages were stained with 0.2 ug Purified Anti-Mouse F4/80 Antibody[CI:A3-1](Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD86 Antibody[GL-1] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Rat IgG Secondary Antibody.