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Antikörper

Purified Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1], Functional Grade

Produktgrößen
100 ug
£89,00
E-AB-F11120-100UG
1 mg
£171,00
E-AB-F11120-1MG
5 mg
£490,00
E-AB-F11120-5MG
25 mg
£1515,00
E-AB-F11120-25MG
50 mg
£2247,00
E-AB-F11120-50MG
100 mg
£3211,00
E-AB-F11120-100MG
Über dieses Produkt
SKU:
E-AB-F11120
Zusätzliche Namen:
B220
Anwendung:
Depletion, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
RA3.3A 1/6.1
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker, however, CD19 may be more appropriate for B cell specificity. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
CD45R/B220
Isotyp:
IgM, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody