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Antikörper

AF/LE Purified Anti-Human CD8a Antibody[OKT-8]

Produktgrößen
25 ug
£66,00
E-AB-F11100-25UG
100 ug
£89,00
E-AB-F11100-100UG
1 mg
£171,00
E-AB-F11100-1MG
5 mg
£490,00
E-AB-F11100-5MG
25 mg
£1515,00
E-AB-F11100-25MG
50 mg
£2247,00
E-AB-F11100-50MG
100 mg
£3211,00
E-AB-F11100-100MG
Über dieses Produkt
SKU:
E-AB-F11100
Zusätzliche Namen:
CD8A;MAL;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
OKT-8
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Host:
Mouse
Immunogen:
CD8|Recombinant Human CD8 protein
Isotyp:
IgG2a, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:D0Ken1