AF/LE Purified Anti-Mouse CD115/CSF-1R Antibody[AFS98]
Produktgrößen
25 ug
£66,00
E-AB-F11070-25UG
100 ug
£89,00
E-AB-F11070-100UG
1 mg
£171,00
E-AB-F11070-1MG
5 mg
£490,00
E-AB-F11070-5MG
25 mg
£1515,00
E-AB-F11070-25MG
50 mg
£2247,00
E-AB-F11070-50MG
100 mg
£3211,00
E-AB-F11070-100MG
Über dieses Produkt
- SKU:
- E-AB-F11070
- Zusätzliche Namen:
- CD115;CSF-1 receptor (EC:2.7.10.1);CSF-1-R;CSF-1R;Csf1r;Csfmr;Fms;M-CSF-R;Macrophage colony-stimulating factor 1 receptor;Proto-oncogene c-Fms
- Anwendung:
- Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- AFS98
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
- Host:
- Rat
- Immunogen:
- CD115|Recombinant Mouse CD115 protein
- Isotyp:
- IgG2a, kappa
- Reinheit:
- >98%
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:nDGCC0