APC Anti-Mouse CD103 Antibody[M290]
Produktgrößen
25 ug
£117,00
E-AB-F1090UE-25UG
100 ug
£217,00
E-AB-F1090UE-100UG
Über dieses Produkt
- SKU:
- E-AB-F1090UE
- Zusätzliche Namen:
- CD103;Integrin alpha M290;Integrin alpha-E;Itgae
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- M290
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- CD103 is a type I transmembrane glycoprotein known as A AlphaE integrin or Integrin A AlphaIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-B Beta stimulation. In association with integrin B Beta7, CD103 is expressed as A AlphaE/B Beta7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
- Host:
- Rat
- Immunogen:
- CD103
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-apc_anti_mouse_cd103_antibody[m290]-e_ab_f1090ue