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Antikörper

Elab Fluor[R] 488 Anti-Human CD40 Antibody[3A8]

Produktgrößen
20 tests
£109,00
E-AB-F1037L-20TESTS
100 tests
£220,00
E-AB-F1037L-100TESTS
2 x 100 tests
£305,00
E-AB-F1037L-2X100TESTS
Über dieses Produkt
SKU:
E-AB-F1037L
Zusätzliche Namen:
B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5
Anwendung:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
3A8
Klonalität:
Monoclonal
Konjugat:
Elab Fluor® 488
Konzentration:
5 ul/test
Weitere Details:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Host:
Mouse
Immunogen:
CD40
Isotyp:
IgG2a, kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody