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Antikörper

AF/LE Purified Anti-Mouse CD162 Antibody[4RA10]

Produktgrößen
25 ug
£66,00
E-AB-F10340-25UG
100 ug
£89,00
E-AB-F10340-100UG
1 mg
£171,00
E-AB-F10340-1MG
5 mg
£490,00
E-AB-F10340-5MG
25 mg
£1515,00
E-AB-F10340-25MG
50 mg
£2247,00
E-AB-F10340-50MG
100 mg
£3211,00
E-AB-F10340-100MG
Über dieses Produkt
SKU:
E-AB-F10340
Zusätzliche Namen:
CD162;P-selectin glycoprotein ligand 1;PSGL-1;Selectin P ligand;Selplg
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
4RA10
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.
Host:
Rat
Immunogen:
CD162
Isotyp:
IgG1, kappa
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:De5CeD
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD335 Antibody[29A1.4] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse NK1.1 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse peripheral blood were stained with 0.2 ug AF/LE Purified Anti-Mouse CD41 Antibody[MWReg301] (Right) and 0.2 ug Rat IgG, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Rat Ter-119 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD335 Antibody[29A1.4] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse NK1.1 PE-conjugated Monoclonal Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse Ly6A/E Antibody[D7] (Right) and 0.2 ug Rat Ig2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD5 Antibody[53-7.3] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody, then anti-Mouse CD3 PE-conjugated Monoclonal Antibody.