PE Anti-Mouse CD122/IL-2RB Antibody[5H4]
Produktgrößen
25 ug
£106,00
E-AB-F1029UD-25UG
100 ug
£197,00
E-AB-F1029UD-100UG
Über dieses Produkt
- SKU:
- E-AB-F1029UD
- Zusätzliche Namen:
- IL-2R subunit beta,CD122,High affinity IL-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2RB,Il2rb,Interleukin-2 receptor subunit beta,p70-75
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 5H4
- Klonalität:
- Monoclonal
- Konjugat:
- R-PE
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- CD122 is a 70-75 kD IL-2 receptor B Beta chain also known as IL-2RB Beta, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2RB Beta chain can combine with either the common G Gamma subunit (G Gammac, CD132) alone or with the G Gammac subunit and the IL-2RA Alpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
- Host:
- Rat
- Immunogen:
- CD122
- Isotyp:
- IgG2a, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:0irLy9