APC Anti-Mouse CD54 Antibody[YN1/1.7.4]
Produktgrößen
25 ug
£106,00
E-AB-F1018UE-25UG
100 ug
£182,00
E-AB-F1018UE-100UG
Über dieses Produkt
- SKU:
- E-AB-F1018UE
- Zusätzliche Namen:
- CD54;Icam-1;Icam1;Intercellular adhesion molecule 1;MALA-2;MyD10
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- YN1/1.7.4
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 0.2 mg/ml
- Weitere Details:
- CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
- Host:
- Rat
- Immunogen:
- CD54
- Isotyp:
- IgG2b, kappa
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:1.7.4]-e_ab_f1018ue