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Antikörper

Purified Anti-Mouse CD54 Antibody[YN1/1.7.4], Functional Grade

Produktgrößen
100 ug
£89,00
E-AB-F10180-100UG
1 mg
£171,00
E-AB-F10180-1MG
5 mg
£490,00
E-AB-F10180-5MG
25 mg
£1515,00
E-AB-F10180-25MG
50 mg
£2247,00
E-AB-F10180-50MG
100 mg
£3211,00
E-AB-F10180-100MG
Über dieses Produkt
SKU:
E-AB-F10180
Zusätzliche Namen:
CD54,Icam-1,Icam1,Intercellular adhesion molecule 1,MALA-2,MyD10
Anwendung:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
YN1/1.7.4
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Rat
Immunogen:
Recombinant Mouse CD54 protein
Isotyp:
IgG2b, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
C57/BL6 Mouse splenocytes were stained with 0.2 ug Purified Anti-Mouse CD54 Antibody[YN1/1.7.4], Functional Grade (Right) and 0.2 ug Rat IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD58 Antibody[TS2/9.1] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood granulocyte were stained with 0.2 ug AF/LE Purified Anti-Human CD32 Antibody[IV-3] (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood Granulocytes were stained with 0.2 ug Purified Anti-Human CD15/SSEA-1 Antibody[HI98] (Right) and 0.2 ug Mouse IgM, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Mouse IgM Secondary Antibody.
Human peripheral blood red blood cells were stained with 0.2 ug Purified Anti-Human CD235 Antibody[HIR2] (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.