AF/LE Purified Anti-Mouse CD54 Antibody[YN1/1.7.4]
Produktgrößen
25 ug
£66,00
E-AB-F10180-25UG
100 ug
£89,00
E-AB-F10180-100UG
1 mg
£171,00
E-AB-F10180-1MG
5 mg
£490,00
E-AB-F10180-5MG
25 mg
£1515,00
E-AB-F10180-25MG
50 mg
£2247,00
E-AB-F10180-50MG
100 mg
£3211,00
E-AB-F10180-100MG
Über dieses Produkt
- SKU:
- E-AB-F10180
- Zusätzliche Namen:
- CD54;Icam-1;Icam1;Intercellular adhesion molecule 1;MALA-2;MyD10
- Anwendung:
- Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- YN1/1.7.4
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
- Host:
- Rat
- Immunogen:
- CD54|Recombinant Mouse CD54 protein
- Isotyp:
- IgG2b, kappa
- Reinheit:
- >98%
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:KyT0OC