CASP1 Polyclonal Antibody
Produktgrößen
60 ul
£235,00
E-AB-93322-60UL
120 ul
£346,00
E-AB-93322-120UL
200 ul
£541,00
E-AB-93322-200UL
Über dieses Produkt
- SKU:
- E-AB-93322
- Zusätzliche Namen:
- ICE; IL1BC; P45; caspase-1;CASP1
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CASP1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-casp1_polyclonal_antibody-e_ab_93322