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Antikörper

HLA-DPB1 Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-93211-60UL
120 ul
£317,00
E-AB-93211-120UL
200 ul
£492,00
E-AB-93211-200UL
Über dieses Produkt
SKU:
E-AB-93211
Zusätzliche Namen:
DP beta 1,DPB1,HLA-DP,HLA-DP1B,HLA-DPB,HLA-DPB1,class II,major histocompatibility complex
Anwendung:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
A synthetic peptide of human HLA-DPB1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody