(KO Validated) CDK4 Polyclonal Antibody
Produktgrößen
60 ul
£234,00
E-AB-93172-60UL
120 ul
£350,00
E-AB-93172-120UL
200 ul
£533,00
E-AB-93172-200UL
Über dieses Produkt
- SKU:
- E-AB-93172
- Zusätzliche Namen:
- CDK4,CMM3,PSK-J3
- Anwendung:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human CDK4
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-(ko_validated)_cdk4_polyclonal_antibody-e_ab_93172