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Antikörper

PKC zeta Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-92669-60UL
120 ul
£317,00
E-AB-92669-120UL
200 ul
£492,00
E-AB-92669-200UL
Über dieses Produkt
SKU:
E-AB-92669
Zusätzliche Namen:
PKC-ZETA,PKC2,PRKCZ
Anwendung:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human PKC zeta
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody