MASP1 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-92666-60UL
120 ul
£317,00
E-AB-92666-120UL
200 ul
£492,00
E-AB-92666-200UL
Über dieses Produkt
- SKU:
- E-AB-92666
- Zusätzliche Namen:
- 3MC1,CRARF,CRARF1,MAP1,MASP,MASP1,MASP3,MAp44,PRSS5,RaRF
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human MASP1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-masp1_polyclonal_antibody-e_ab_92666