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Antikörper

PMEL Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-92644-60UL
120 ul
£317,00
E-AB-92644-120UL
200 ul
£492,00
E-AB-92644-200UL
Über dieses Produkt
SKU:
E-AB-92644
Zusätzliche Namen:
D12S53E,ME20,ME20-M,ME20M,P1,P100,PMEL,PMEL17,SI,SIL,SILV,gp100
Anwendung:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human PMEL
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody