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Antikörper

CCR1 Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-92022-60UL
120 ul
£317,00
E-AB-92022-120UL
200 ul
£492,00
E-AB-92022-200UL
Über dieses Produkt
SKU:
E-AB-92022
Zusätzliche Namen:
CCR1,CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1
Anwendung:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Host:
Rabbit
Immunogen:
A synthetic peptide of human CCR1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody