TNFRSF13C Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-90789-60UL
120 ul
£317,00
E-AB-90789-120UL
200 ul
£492,00
E-AB-90789-200UL
Über dieses Produkt
- SKU:
- E-AB-90789
- Zusätzliche Namen:
- BAFF-R,BAFFR,BROMIX,CD268,CVID4,TNFRSF13C,prolixin
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human TNFRSF13C
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-tnfrsf13c_polyclonal_antibody-e_ab_90789