RFTN1 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-90163-60UL
120 ul
£317,00
E-AB-90163-120UL
200 ul
£492,00
E-AB-90163-200UL
Über dieses Produkt
- SKU:
- E-AB-90163
- Zusätzliche Namen:
- MIG2,PIB10,PIG9,RAFTLIN,RFTN1,raftlin
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Involved in protein trafficking via association with clathrin and AP2 complex. Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity. May regulate B-cell antigen receptor-mediated signaling. May play a pivotal role in the formation and/or maintenance of lipid rafts.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human RFTN1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-rftn1_polyclonal_antibody-e_ab_90163