Recombinant XBP1 Monoclonal Antibody
Produktgrößen
50 ul
£198,00
E-AB-81622-50UL
100 ul
£291,00
E-AB-81622-100UL
Über dieses Produkt
- SKU:
- E-AB-81622
- Zusätzliche Namen:
- TREB5,Tax responsive element binding protein 5,Tax-responsive element-binding protein 5,X box binding protein 1,X box binding protein 2,X-box-binding protein 1,XBP 1,XBP-1,XBP1,XBP2
- Anwendung:
- Western Blot
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- translate.label.attr.clone:
- R04-3E2
- Klonalität:
- Monoclonal
- Konzentration:
- 300 ug/ml
- Weitere Details:
- This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human XBP1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-recombinant_xbp1_monoclonal_antibody-e_ab_81622