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Antikörper

Recombinant LRP1 Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81579-50UL
100 ul
£291,00
E-AB-81579-100UL
Über dieses Produkt
SKU:
E-AB-81579
Zusätzliche Namen:
A2MR,APOER,APR,CD91,IGFBP3R,KPA,LRP,LRP1,LRP1A,TGFBR5
Anwendung:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R09-4E8
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
Host:
Rabbit
Immunogen:
A synthetic peptide of human LRP1
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody