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Antikörper

Recombinant ALIX Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81456-50UL
100 ul
£291,00
E-AB-81456-100UL
Über dieses Produkt
SKU:
E-AB-81456
Zusätzliche Namen:
AIP1,ALIX,DRIP4,HP95,PDCD6IP
Anwendung:
Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R03-8C2
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
Host:
Rabbit
Immunogen:
Recombinant protein of human ALIX
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Hamster, Human, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody