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Antikörper

Recombinant c Myc Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81443-50UL
100 ul
£291,00
E-AB-81443-100UL
Über dieses Produkt
SKU:
E-AB-81443
Zusätzliche Namen:
AU016757,Avian myelocytomatosis viral oncogene homolog,Class E basic helix-loop-helix protein 39,MRTL,MYC,MYCC,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,bHLHe39,c Myc,myc-related translation/localization regulatory factor
Anwendung:
Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R05-5E2
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Host:
Rabbit
Immunogen:
A synthetic peptide of human c-Myc
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody