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Antikörper

Recombinant Bax Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81433-50UL
100 ul
£291,00
E-AB-81433-100UL
Über dieses Produkt
SKU:
E-AB-81433
Zusätzliche Namen:
Apoptosis regulator BAX,BAX,BAXA,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,BCL2L4,Bax-protein,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,Bcl2-L-4,membrane isofor
Anwendung:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R03-1D3
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
BAX,also named as BCL2L4,is a pro-apoptotic member of the Bcl-2 protein family,which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells,but accumulates on the outer mitochondrial membrane upon apoptosis induction . BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane,which leads to the release of cytochrome c from mitochondria . The expression of BAX is upregulated by the tumor suppressor protein p53,and BAX has been shown to be involved in p53-mediated apoptosis .
Host:
Rabbit
Immunogen:
A synthetic peptide of human Bax
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody