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Antikörper

Recombinant IKB alpha Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81430-50UL
100 ul
£291,00
E-AB-81430-100UL
Über dieses Produkt
SKU:
E-AB-81430
Zusätzliche Namen:
I kappa B alpha,I-kappa-B-alpha,IKB alpha,IKBA,IKBalpha,IkB-alpha,IkappaBalpha,MAD 3,MAD3,NF kappa B inhibitor alpha,NFKBI
Anwendung:
Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R06-9E9
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,alpha (NFKBIA,synonyms: IKBA,MAD-3,NFKBI). NFKB1 or NFKB2 is bound to REL,RELA ,or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB),which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA,or IKBKB) marks them for destruction via the ubiquitination pathway,thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.
Host:
Rabbit
Immunogen:
A synthetic peptide of human IKB alpha
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody