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Antikörper

Recombinant E Cadherin Monoclonal Antibody

Produktgrößen
50 ul
£198,00
E-AB-81424-50UL
100 ul
£291,00
E-AB-81424-100UL
Über dieses Produkt
SKU:
E-AB-81424
Zusätzliche Namen:
Arc 1,CADH1,CAM 120/80,CD 324,CD324,CD324 antigen,CDHE,Cadherin 1,Cadherin1,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin,cadherin 1 type 1 E-cadherin,cdh1,epithelial calcium dependant adhesion protein
Anwendung:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
translate.label.attr.clone:
R07-4F1
Klonalität:
Monoclonal
Konzentration:
300 ug/ml
Weitere Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Host:
Rabbit
Immunogen:
A synthetic peptide of human E Cadherin
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody