CASP3 Polyclonal Antibody
Produktgrößen
60 ul
£198,00
E-AB-70388-60UL
120 ul
£291,00
E-AB-70388-120UL
200 ul
£430,00
E-AB-70388-200UL
Über dieses Produkt
- SKU:
- E-AB-70388
- Zusätzliche Namen:
- A830040C14Rik;Apopain;CASP-3;CASP3;CC3;CPP-32;CPP32;CPP32B;Casp3a;Caspase 3;Caspase-3 subunit p12;Cysteine p;apoptosis-related cysteine peptidase;apoptosis-related cysteine protease;apoptosis-related cysteine protease a
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 500 ug/ml
- Weitere Details:
- Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs MW of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse caspase3
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-casp3_polyclonal_antibody-e_ab_70388