FAS Polyclonal Antibody
Produktgrößen
60 ul
£198,00
E-AB-70336-60UL
120 ul
£291,00
E-AB-70336-120UL
200 ul
£430,00
E-AB-70336-200UL
Über dieses Produkt
- SKU:
- E-AB-70336
- Zusätzliche Namen:
- ALPS 1A;ALPS1A;APO 1;APO 1 cell surface antigen;APO1;APO1 cell surface antigen;APT 1;APT1;Apo 1 antigen;Apo-1 antigen;Apo1 antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;CD 95;CD 95 antigen;CD95
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse FasL
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-fas_polyclonal_antibody-e_ab_70336