PKM Polyclonal Antibody
Produktgrößen
60 ul
£198,00
E-AB-70274-60UL
120 ul
£291,00
E-AB-70274-120UL
200 ul
£430,00
E-AB-70274-200UL
Über dieses Produkt
- SKU:
- E-AB-70274
- Zusätzliche Namen:
- CTHBP,Cytosolic thyroid hormone binding protein,Cytosolic thyroid hormone-binding protein,KPYM,MGC3932,OIP 3,OIP-3,OIP3,OPA interacting protein 3,Opa-interacting protein 3,PK,PK muscle type,PK2,PK3,PKM,PKM2,Pyruvat,Pyruvate kinase 2/3,muscle type,p58,pykm
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 440 ug/ml
- Weitere Details:
- PKM2,also named as OIP3,PK2,PK3,PKM,p58,THBP1,CTHBP and Tumor M2-PK,belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP,generating ATP. It stimulates POU5F1-mediated transcriptional activation. PKM2 plays a general role in caspase independent cell death of tumor cells. The activity of the M2 isoform (but not the M1 isoform) can be inhibited by tyrosine kinase signalling in tumourcells.The primary pyruvate kinase isoform before tumour development is PK-M1, however,the primary isoform from four independent tumours is PK-M2. PKM2,Pyruvate kinase isozymes M1/M2,has 2 isoforms .The immunogen of this antibody is M2 isoform,also called PKM2.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse PKM2
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-pkm_polyclonal_antibody-e_ab_70274