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Antikörper

E-Cadherin Monoclonal Antibody

Produktgrößen
60 ul
£198,00
E-AB-70249-60UL
120 ul
£291,00
E-AB-70249-120UL
200 ul
£430,00
E-AB-70249-200UL
Über dieses Produkt
SKU:
E-AB-70249
Zusätzliche Namen:
Arc 1;CADH1;CAM 120/80;CD 324;CD324;CD324 antigen;CDHE;Cadherin 1;Cadherin1;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin;cadherin 1 type 1 E-cadherin;cdh1;epithelial calcium dependant adhesion protein
Anwendung:
Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
EC125D
Klonalität:
Monoclonal
Konzentration:
1.6 mg/ml
Weitere Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Host:
Mouse
Immunogen:
Recombinant protein corresponding to MouseE-cadherin
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody