FOXO1 Polyclonal Antibody
Produktgrößen
60 ul
£198,00
E-AB-70143-60UL
120 ul
£291,00
E-AB-70143-120UL
200 ul
£430,00
E-AB-70143-200UL
Über dieses Produkt
- SKU:
- E-AB-70143
- Zusätzliche Namen:
- Drosophila;FKH 1;FKH1;FKHR;FOXO1;Forkhead;Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma);Forkhead box O1;Forkhead box protein O1;Forkhead box protein O1A;Forkhead in rhabdomyosarcoma;FoxO transcription factor;foxo1;homolog of;in rhabdomyosarcoma
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.58 mg/ml
- Weitere Details:
- FOXO1,also named as FOXO1A,FKHR and FKH1,is a member of the FOXO subfamily of Forkhead transcription factors. FOXO1 is a transcription factor which acts as a regulator of cell responses to oxidative stress. FOXO1 interacts with LRPPRC and SIRT1. In the presence of KIRT1,FOXO1 mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. FOXO1 contains three predicted protein kinase B phosphorylation sites (Thr-24,Ser-256,and Ser-319) that are conserved in other FOXO proteins. The t(2;13) and the variant t(1;13) translocations generate PAX3/FKHR and PAX7/FKHR fusion proteins respectively. The resulting protein is a transcriptional activator. Defects in FOXO1 are a cause of rhabdomyosarcoma type 2 (RMS2).
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse FOXO1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-foxo1_polyclonal_antibody-e_ab_70143