p27 Polyclonal Antibody
Produktgrößen
60 ul
£198,00
E-AB-70069-60UL
120 ul
£291,00
E-AB-70069-120UL
200 ul
£430,00
E-AB-70069-200UL
Über dieses Produkt
- SKU:
- E-AB-70069
- Zusätzliche Namen:
- AA408329,AI843786,CDKN 1B,CDKN 4,CDKN1B,CDKN4,CDN1B,Cdki1b,Cyclin Dependent Kinase Inhibitor 1B,Cyclin dependent kinase inhibitor p27,Cyclin-dependent kinase inhibitor 1B,Cyclin-dependent kinase inhibitor 1B (p27,Cyclin-dependent kinase inhibitor p2,Kip1)
- Anwendung:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 0.89 mg/ml
- Weitere Details:
- This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse P27 KIP1
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-p27_polyclonal_antibody-e_ab_70069