c-Myc Polyclonal Antibody
Produktgrößen
60 ul
£235,00
E-AB-68295-60UL
120 ul
£346,00
E-AB-68295-120UL
200 ul
£541,00
E-AB-68295-200UL
Über dieses Produkt
- SKU:
- E-AB-68295
- Zusätzliche Namen:
- MRTL,MYC,MYCC,bHLHe39,c-Myc
- Anwendung:
- ELISA, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human c-Myc
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-c_myc_polyclonal_antibody-e_ab_68295