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Antikörper

PDE6A Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-67927-60UL
120 ul
£317,00
E-AB-67927-120UL
200 ul
£492,00
E-AB-67927-200UL
Über dieses Produkt
SKU:
E-AB-67927
Zusätzliche Namen:
CGPR-A,PDE6A,PDEA,RP43
Anwendung:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human PDE6A (NP_000431.2).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody