APLP2 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-67662-60UL
120 ul
£317,00
E-AB-67662-120UL
200 ul
£492,00
E-AB-67662-200UL
Über dieses Produkt
- SKU:
- E-AB-67662
- Zusätzliche Namen:
- APLP-2,APLP2,APPH,APPL2,CDEBP
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human APLP2 (NP_001135750.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-aplp2_polyclonal_antibody-e_ab_67662