INS Polyclonal Antibody
Produktgrößen
60 ul
£235,00
E-AB-67409-60UL
120 ul
£346,00
E-AB-67409-120UL
200 ul
£541,00
E-AB-67409-200UL
Über dieses Produkt
- SKU:
- E-AB-67409
- Zusätzliche Namen:
- IDDM;IDDM1;IDDM2;ILPR;INS;IRDN;Insulin;MODY10;insulin
- Anwendung:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human INS (NP_000198.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ins_polyclonal_antibody-e_ab_67409