DNA polymerase eta Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-67345-60UL
120 ul
£317,00
E-AB-67345-120UL
200 ul
£492,00
E-AB-67345-200UL
Über dieses Produkt
- SKU:
- E-AB-67345
- Zusätzliche Namen:
- POLH,RAD30,RAD30A,XP-V,XPV
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human DNA polymerase eta (NP_006493.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-dna_polymerase_eta_polyclonal_antibody-e_ab_67345