Complement Factor B Polyclonal Antibody
Produktgrößen
60 ul
£235,00
E-AB-67031-60UL
120 ul
£346,00
E-AB-67031-120UL
200 ul
£541,00
E-AB-67031-200UL
Über dieses Produkt
- SKU:
- E-AB-67031
- Zusätzliche Namen:
- AHUS4;ARMD14;BF;BFD;CFAB;CFB;CFBD;FB;FBI12;GBG;H2-Bf;PBF2
- Anwendung:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human Complement Factor B (NP_001701.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-complement_factor_b_polyclonal_antibody-e_ab_67031