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Antikörper

(KO Validated) DNMT1 Polyclonal Antibody

Produktgrößen
60 ul
£234,00
E-AB-66916-60UL
120 ul
£350,00
E-AB-66916-120UL
200 ul
£533,00
E-AB-66916-200UL
Über dieses Produkt
SKU:
E-AB-66916
Zusätzliche Namen:
ADCADN,AIM,CXXC9,DNMT,DNMT1,HSN1E,MCMT,m.HsaI
Anwendung:
Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant protein of human DNMT1.
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody