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Antikörper

FLNA Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-66787-60UL
120 ul
£317,00
E-AB-66787-120UL
200 ul
£492,00
E-AB-66787-200UL
Über dieses Produkt
SKU:
E-AB-66787
Zusätzliche Namen:
ABP-280,ABPX,CSBS,CVD1,FLN,FLN-A,FLN1,FLNA,FMD,MNS,NHBP,OPD,OPD1,OPD2,XLVD,XMVD,filamin-A
Anwendung:
Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic peptide of human FLNA (NP_001104026.1).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody