TAZ Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-66586-60UL
120 ul
£317,00
E-AB-66586-120UL
200 ul
£492,00
E-AB-66586-200UL
Über dieses Produkt
- SKU:
- E-AB-66586
- Zusätzliche Namen:
- AGMX1,AT,ATK,BPK,BTK,Bruton tyrosine kinase,IMD1,PSCTK1,TAZ,WWTR1,XLA
- Anwendung:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial-mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human TAZ (NP_056287.1).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-taz_polyclonal_antibody-e_ab_66586