UNC13B Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-66572-60UL
120 ul
£317,00
E-AB-66572-120UL
200 ul
£492,00
E-AB-66572-200UL
Über dieses Produkt
- SKU:
- E-AB-66572
- Zusätzliche Namen:
- MUNC13,UNC13,UNC13B,Unc13h2
- Anwendung:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human UNC13B (NP_006368.3).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-unc13b_polyclonal_antibody-e_ab_66572