CAV1 Polyclonal Antibody
Produktgrößen
60 ul
£217,00
E-AB-66490-60UL
120 ul
£317,00
E-AB-66490-120UL
200 ul
£492,00
E-AB-66490-200UL
Über dieses Produkt
- SKU:
- E-AB-66490
- Zusätzliche Namen:
- BSCL3,CAV1,CGL3,LCCNS,MSTP085,PPH3,VIP21
- Anwendung:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CAV1 (NP_001744.2).
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-cav1_polyclonal_antibody-e_ab_66490