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Antikörper

LRP6 Polyclonal Antibody

Produktgrößen
60 ul
£217,00
E-AB-66414-60UL
120 ul
£317,00
E-AB-66414-120UL
200 ul
£492,00
E-AB-66414-200UL
Über dieses Produkt
SKU:
E-AB-66414
Zusätzliche Namen:
ADCAD2,LRP6,STHAG7
Anwendung:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human LRP6 (NP_002327.2).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody