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Antikörper

NFkB p100 / p52 Polyclonal Antibody

Produktgrößen
60 ul
£235,00
E-AB-65807-60UL
120 ul
£346,00
E-AB-65807-120UL
200 ul
£541,00
E-AB-65807-200UL
Über dieses Produkt
SKU:
E-AB-65807
Zusätzliche Namen:
CVID10,H2TF1,LYT-10,LYT10,NF-kB2,p100,p49/p100,p52
Anwendung:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human NFkB p100 / p52 (NP_002493.3).
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody